Scientists identify three blood biomarkers for early preeclampsia detection

Preeclampsia, a hypertensive disorder of pregnancy that remains among the leading causes of maternal death worldwide, has long resisted early detection — its clinical signs often arriving only after harm is already done. Researchers have now identified three blood-based molecular markers, MAPK8, CSNK1E, and NOTUM, rooted in a cellular pathway governing placental health, that together distinguish preeclamptic from healthy pregnancies with roughly 92 percent accuracy. The work does not yet offer a clinical test, but it suggests that the biological story of this disease can be read in the bloodst