Scientists Identify DDX6 as Hidden Switch Enabling Cancer to Evade Immune System

In the long struggle between the body's defenses and the cells that would subvert them, science has uncovered another layer of concealment: a protein called DDX6 that silences the molecular alarms cancer cells should trigger. Researchers at the Cancer Science Institute of Singapore, publishing in Science Immunology in June 2026, revealed how this RNA helicase works alongside a known enzyme to keep tumors invisible to the immune system. The discovery not only names a new target for therapy but overturns longstanding assumptions about how RNA editing shapes immunity — suggesting that what was th