Doctors identify breast cancer patients at risk of recurrence through dormant 'sleeper cells'

Approximately 42,680 people die from breast cancer annually in the U.S., and 30% of patients experience recurrence after initial treatment, which is currently incurable.

For generations, breast cancer survivors have endured a quiet uncertainty after treatment ends — a waiting that medicine could neither shorten nor resolve. Researchers at the University of Pennsylvania have now identified the biological agents of that uncertainty: dormant 'sleeper cells' hiding in bone marrow, capable of awakening into incurable disease years or decades later. In a clinical trial, targeted drugs cleared these cells from 80 percent of participants, with only two recurrences observed — suggesting that the long era of passive surveillance may be giving way to something more merci

Doctors identify breast cancer patients at risk of recurrence through dormant 'sleeper cells'

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